Glucose-6-phosphate-dependent phosphoryl flow through the Uhp two-component regulatory system
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منابع مشابه
Glucose-6-phosphate-dependent phosphoryl flow through the Uhp two-component regulatory system.
Expression of the UhpT sugar-phosphate transporter in Escherichia coli is regulated at the transcriptional level via the UhpABC signalling cascade. Sensing of extracellular glucose 6-phosphate (G6P), by membrane-bound UhpC, modulates a second membrane-bound protein, UhpB, resulting in autophosphorylation of a conserved histidine residue in the cytoplasmic (transmitter) domain of the latter. Sub...
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Membrane vesicles were characterized for their ability to specifically bind [14C]glucose 6-phosphate. Membranes prepared from a strain carrying a ColE1 uhp hybrid plasmid showed significantly enhanced glucose 6-phosphate binding. It is hypothesized that glucose 6-phosphate binding to these membranes is due to a uhpR-directed, membrane-bound receptor which functions in regulation of the inducibl...
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Description Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is the most common human enzyme deficiency that mainly affects the red blood cells (RBCs). A defect in G6PD enzyme leads to the destruction of premature RBCs causing hemolytic anemia because the body can not compensate the destroyed RBCs. Thus, the affected individuals show jaundice (paleness, yellowing of the skin and whites of th...
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ژورنال
عنوان ژورنال: Microbiology
سال: 2001
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-147-12-3345